Librería Servicio Médico

Author:  Laurie K. McCauley / Martha J. Somerman

Language: English

Finishing:Hardcover , 392 pages

ISBN:978-0470958339

Edition: 1/2012

Description:

Mineralized Tissues in Oral and Craniofacial Science is a major comprehensive update on knowledge in the field of mineralized tissues in the oral and craniofacial region. Drs. McCauley and Somerman assembled an international team of researchers and clinicians, offering a global perspective on the current knowledge in this field. Basic and clinical correlates reinforce the significance of research to clinical diagnoses and therapies, written in a manner that lends easily to their use for case study teaching venues.

Section 1 features the many aspects of bone in the craniofacial region, including embryology, cell biology, and stem cell biology. Section 2 focuses on teeth-tooth development, dentin, enamel, cementum, and tooth regeneration. Section 3 discusses the interaction between bones and teeth, including those associated with inflammatory processes, periodontal ligaments, biomechanics, and other impact factors-such as nutrition, metabolic bone diseases and therapeutic modalities.

The novel approach of linking the basic principles of the cell and molecular biology of hard tissues to clinical correlates will appeal to readers at all levels of their research careers, both students and faculty; faculty interested in a comprehensive text for reference; and  clinicians interested in the biologic aspects of bones and teeth.

Author information:

Laurie K. McCauley, DDS, PhD is the William K. and Mary Anne Najjar Professor and Chair of the Department of Periodontics and Oral Medicine, and Professor in the Department of Pathology at the University of Michigan in Ann Arbor, Michigan.

Martha J. Somerman, DDS, PhD, formerly Dean and Professor, University of Washington School of Dentistry, is currently the Director of the National Institute of Dental and Craniofacial Research, and Chief, Laboratory for Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases at the National Institutes of Health in Bethesda, Maryland.

Table of contents:

• Contributors vii
• Preface xv
• Acknowledgments xvii
• Foreword xix

Section 1 Bones of the oral-dental and craniofacial complex 1

• Embryology of craniofacial bones
• Clinical correlate: cleft lip and palate 
• Cell and molecular biology of the osteoclast and bone resorption
• Clinical correlate: osteopetrosis 
• Clinical correlate: CLCN7-associated autosomal recessive osteopetrosis 
• Osteoblasts of craniofacial bone 
• Clinical correlate: cleidocranial dysplasia
• Cell biology of craniofacial bone: osteocytes
• Clinical correlate: Van Buchem disease
• Stem cell biology in the craniofacial apparatus 
• Clinical correlate: stem cell therapy for craniofacial bone regeneration
• Extracellular matrix and mineralization of craniofacial bone
• Clinical correlate: osteogenesis imperfecta

Section 2 Teeth 117

• Tooth development 
• Clinical correlate: tooth agenesis
• Dentin
• Clinical correlate: dentinogenesis imperfecta, restorative procedures, and caries
• Enamel fabrication: the story of amelogenesis
• 19 Clinical correlate: amelogenesis imperfecta 
• Cementum 
• Clinical correlate: case study of identical twins with cementum and periodontal defects resulting from odontohypophosphatasia 
• Dental engineering: tooth regeneration
• Clinical correlate: periodontal regeneration
• Clinical correlate: natural tooth regeneration
• Clinical correlate: regenerative endodontics in an immature tooth with pulpal necrosis and periapical pathosis 

Section 3 Bones and teeth 217

• Bone and tooth interface: periodontal ligament 
• Clinical correlate: two cases of destructive periodontal disease
• Periodontal disease and infl ammationinduced bone remodeling 
• Clinical correlate: endodontic lesions
• Biomechanics of teeth in bone: function, movement, and prosthetic rehabilitation
• Clinical correlate: biomechanics of teeth in bone
• Impact of metabolic bone disease on craniofacial bones and teeth
• Clinical correlate: renal osteodystrophy 
• Mineral metabolism and its impact on craniofacial bones and teeth
• Clinical correlate: mineral metabolism and disruption of dentoalveolar development in a case of craniometaphyseal dysplasia (CMD)
• Sun, nutrition, and the mineralization of bones and teeth 
• Clinical correlate: vitamin D deficiency 
• Impact of therapeutic modalities on craniofacial bones and teeth
• Clinical correlate: osteoradionecrosis of the jaws (ORN) 

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