Librería Servicio Médico

Author : Ajay Kumar Mishra

Language: English

Finishing : Hardcover, 286 pages

ISBN : 978-1-118-41409-5

Edition Number: 2013

Description:

This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.

Table Of Contents:

Preface xv

Part 1: Nanomedicine 1
1 High-technology Therapy Using Biomolecules or Synthetic Compounds for HIV Inhibition 3
Elvis Fosso-Kankeu, Pascaline Fontehand Ajay K.Mishra

• 1.1 Gene Therapy Including RNAHigh-Technology Against HIV 4
• 1.2 Metals and HIV Therapy 16
• 1.3 Conclusions 26
• References 27

2 Emerging Nanomedicine Approaches for Osteochondral Tissue Regeneration 39
Author Lineis Missing

• 2.1 Introduction 39
• 2.2 Emerging NanomedicineApproaches 42
• References 54

3 Synthesis of Poly(Methacrylate) Encapsulated Magnetite Nanoparticles via Phosphonic Acid Anchoring Chemistry and Its Applications Toward Biomedicine 63
B. Kothandapaniand Ajay K. Mishra

• 3.1 Introduction 64
• 3.2 Synthesis of Magnetite Nanoparticles 73
• 3.3 Application in Biomedical Fields 82
• 3.4 Conclusions 84
• References 85

4 Potentiometric PVC Membrane Sensors and Their Analytical Applications in Pharmaceuticals and Environmental Samples at Micro- and Nano-level 87
Gamal Abel-Hafiz Mostafa

• 4.1 Introduction 87
• 4.2 Ion Selective Electrode 88
• 4.3 Glass Membrane Electrode 89
• 4.4 Characteristics of ISE 90
• 4.5 Preparation of PVC Membrane 94
• 4.6 Method of Preparation of the Liquid Membrane ISEs 96
• 4.7 Application of Ion Selective Electrodes in Pharmaceutical and Environmental Analysis Using 97
• 4.8 Conclusion 123
• References 127

5 Bioceramics: Silica-based Organic-Inorganic Hybrid Materials for Medical Applications 135
Sadanand Pandey and Shivani B. Mishra

• 5.1 Introduction 136
• 5.2 Organic-Inorganic Hybrid Materials 141
• 5.3 Tissue Engineering 146
• 5.4 Other Organic-Inorganic Bioceramics for Medical Applications 150
• 5.5 Conclusion 156
• 5.6 Considerations and Future Directions 157
• Acknowledgement 157
• References 158

6 Recent Advances of Multifunctional Nanomedicines 163
Pradeep Pratap Singh and Ambika

• 6.1 Introduction 163
• 6.2 Nanomaterials of Biomedical Interest 164
• 6.3 Target-specificPharmacotherapy: Need for Nanocarrier Delivery Systems 165
• 6.4 Engineering of Pharmaceutical Nanosystems 166
• 6.5 Applications of Pharmaceutical Nanotools 180
• 6.6 Nanotoxicity 181
• 6.7 Future prospects 182
• 6.8 Conclusion 183
• References 184

7 Nanomedicinal Approaches for Diabetes Management 189
Prashant Kumar Raiand Ajay Kumar Mishra

• 7.1 Introduction: The Motivation behind the Chapter 189
• 7.2 Type of Diabetes 191
• 7.3 Treatments for Diabetes 192
• 7.4 Why the Interest in Nanomedicine Research? 193
• 7.5 The Vision of Nanotechnology and its Clinical Applications for Diabetes 194
• 7.6 Summary 195
• Acknowledgements 195
• References 195

8 Polymeric Nanofibersin Regenerative Medicine 197
Narayan Chandra Mishra and Sharmistha Mitra (Majumder)

• 8.1 Introduction 197
• 8.2 Preparation of Nanofibers 199
• 8.3 RecentAdvances onApplication of Polymeric Nanofibersin Regenerative Medicine 201
• 8.4 Conclusions 222
• References 222

Part 2: Drug Delivery and Therapeutics 227
9 Multifunctional Nano/Micro Polymer Capsules as Potential 229
Haider Sami, J. Jaishree, Ashok Kumar and Sri Sivakumar

• 9.1 Introduction 230
• 9.2 Synthesis of Polymer Capsules 232
• 9.3 Properties of Multilayered Polymer Capsules 237
• 9.4 Loading of Therapeutics 239
• 9.5 Stimuli-responsive Polymer Capsules 242
• 9.6 Multifunctional Hybrid Capsules 255
• 9.7 Targeted Polymer Capsules 267
• 9.8 BiomedicalApplications 268
• 9.9 Outlook and Future Prospects 274
• References 274

10 Nanophosphors-Nanogold Immunoconjugates in Isolation of Biomembranes and in Drug Delivery 285
Dwijendra Gupta, Dhruv Kumar, Manish Dwivedi, Vijay Tripathi, Pratibha Phadke-Gupta and Surya Pratap Singh

• 10.1 Introduction 286
• 10.2 Nanoparticle Technology 287
• 10.3 The Versatility of Nanoparticles in Biological Sciences 288
• 10.4 Materials and Methods 293
• 10.5 Nanotags for Bio-labeling and Targeting: Nanophosphors or Quantum Dots 297
• 10.6 AFM Study of CdS and BSATagged ZnS-Mn Nanoparticles 302
• 10.7 Nano-Conjugates in Drug Delivery 304
• 10.8 Nanoparticle-mediated Drug Delivery and Nanotherapeutics 305
• 10.9 The Limitations of QDs 306
• 10.10 Summary 307
• Acknowledgements 308
• References 309

11 Cyclodextrin-based Nanoengineered Drug Delivery System 313
Jaya Lakkakula and Rui Werner Maçedo Krause

• 11.1 Introduction 314
• 11.2 Inclusion Complex Formation 316
• 11.3 Phase Solubility Relationships 318
• 11.4 Effect of Cyclodextrin on Drug Formulation 321
• 11.5 Cyclodextrin-based Drug Delivery 324
• 11.6 Cyclodextrins in Novel Drug Delivery Systems (DDS) 331
• 11.7 Conclusion 335
• Acknowledgements 335
• References 338

12 Medicinal Patches and Drug Nanoencapsulation 343
María H. Lissarrague, Hernan Garate, Melisa E. Lamanna, Norma B. D’Accorso and Silvia N.Goyanes

• 12.1 Introduction 343
• 12.2 Overview of Passive Skin Permeation (Passive Patches) 344
• 12.3 Recent Development on Skin Permeation 357
• 12.4 Drug Encapsulation 361
• 12.5 Triggered Release 369
• 12.6 Conclusions 374
• References 374

13 Dendrimers: AClass of Polymer in the Nanotechnology for the Drug Delivery 379
Sunil K.Singh and Vivek K. Sharma

• 13.1 Introduction 379
• 13.2 Historical Origin of Dendrimers 380
• 13.3 Structure of Dendrimers 381
• 13.4 Terms Used in Dendrimer Chemistry 383
• 13.5 Types of Dendrimers 385
• 13.6 Application of Dendrimers 392
• 13.7 Dendrimers in Oral Drug Delivery 394
• 13.8 Dendrimers in Transdermal Drug Delivery 396
• 13.9 Dendrimers in Ocular Drug Delivery 398
• 13.10 Dendrimers inAnticancer Drug Delivery 399
• 13.11 Dendrimers in Cancer Diagnosis and Treatment 401
• 13.12 Conclusion 411
• References 411

14 Designing Nanocarriers for Drug Delivery 417
Munishwar N. Gupta and Joyeeta Mukherjee

• 14.1 Introduction 417
• 14.2 Sizes, Shapes andAdvantages of Nanomaterials 418
• 14.3 Bioconjugation Strategies 421
• 14.4 Carbon Nanotubes 429
• 14.5 Drug Targeting 434
• 14.6 Future Perspectives 436
• Acknowledgements 437
• References 437

15 Multifunctional Polymeric Micelles for Drug Delivery and Therapeutics 443
Alicia Sawdon and Ching-An Peng

• 15.1 Introduction 443
• 15.2 Composition, Formation and Characterization of Polymeric Micelles 444
• 15.3 Polymeric Micelles for Cancer Chemotherapy 450
• 15.4 Targeting Schemes 457
• 15.5 Polymeric Micelles for Diagnostics and Imaging 465
• 15.6 Conclusions 467
• References 467

16 Nanoparticles-based Carriers for Gene Therapy and Drug Delivery 477
Marketa Ryvolova, Jana Drbohlavova, Kristyna Smerkova, Jana Chomoucka, Pavlina Sobrova,Vojtech Adam, PavelKopel, Jaromir Hubalek and Rene Kizek

• 16.1 Introduction 478
• 16.2 Targeted Delivery 478
• 16.3 Conclusion 494
• References 494

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