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Craniofacial Sutures Development Disease and Treatment - Rice

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Author: D.P. Rice Language: English Finishing: Hardcover, 236 pages ISBN: 978-3-8055-8326-8 Edition Number: 2008 Description: Sutures are more than just fibrous joints between the bones in our skull. They are active growth sites that influence the development, growth and shaping of our face and cranium. When suture development is disrupted, craniosynostosis can result,...

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Medicina

Descripción completa de: Craniofacial Sutures Development Disease and Treatment - Rice

Author: D.P. Rice

Language: English

Finishing: Hardcover, 236 pages

ISBN: 978-3-8055-8326-8

Edition Number: 2008

Description:

Sutures are more than just fibrous joints between the bones in our skull. They are active growth sites that influence the development, growth and shaping of our face and cranium. When suture development is disrupted, craniosynostosis can result, a condition which is characterized by the premature closure of one or more cranial sutures before brain growth is complete and leads to an abnormally shaped skull. In this publication, leading experts in the field, both researchers and clinicians, discuss suture morphogenesis from developmental, evolutionary and genetic perspectives. In addition, an appraisal of the molecular etiology, clinical presentation and treatment of craniosynostosis is presented, as well as an outlook to future areas of study and to innovative therapeutic philosophies.

In this volume craniofacial developmental and evolutionary biologists, oral and maxillofacial surgeons, orthodontists as well as pediatric and plastic surgeons will find a wealth of recent information on the field of craniofacial development, deformity and its treatment.

Contents:

Foreword
Preface
Developmental Anatomy of Craniofacial Sutures
Locate, Condense, Differentiate, Grow and Confront: Developmental Mechanisms Controlling Intramembranous Bone and Suture Formation and Function
Mechanical Influences on Suture Development and Patency
Suture Neontology and Paleontology: The Bases for Where, When and How Boundaries between Bones Have Been Established and Have Evolved
Single Suture Craniosynostosis: Diagnosis and Imaging
Clinical Features of Syndromic Craniosynostosis
Genetics of Craniosynostosis: Genes, Syndromes, Mutations and Genotype-Phenotype Correlations
Roles of FGFR2 and Twist in Human Craniosynostosis: Insights from Genetic Mutations in Cranial Osteoblasts
Fibroblast Growth Factor Signaling in Cranial Suture Development and Pathogenesis
Tgf-β Regulation of Suture Morphogenesis and Growth
The Bmp Pathway in Skull Vault Development
Current Treatment of Craniosynostosis and Future Therapeutic Directions

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